People desire to reduce their weight for a variety of reasons. Keeping a healthy weight improves general quality of life and offers protection against several diseases, such as cancer and heart disease. Reducing excess weight can result in better mental health, more comfort, and increased confidence.
Losing weight, however, can be difficult for many people, especially as they age. Weight gain can be attributed to aspects such as increased stress levels, a slower metabolism, and aging. Your body may not function at its best, so diet and exercise alone might not be enough. Luckily, there is more support available with peptide treatment to help you reach your weight loss objectives.
There is a big market for weight loss drugs these days, and weight loss peptides are just one of the many options. When comparing weight loss peptides to conventional methods, there are benefits and drawbacks. To make these options more accessible for you to understand, we have provided a simplified overview. Please contact IV Vitamin Therapy with any questions you may have.
Peptide-Based Fat Loss Mechanisms
By several methods, they support peptides for fat loss:
Control Of Appetite
Semaglutide and liraglutide are examples of GLP-1 receptor agonists that decrease appetite and increase feelings of fullness, which reduces calorie intake.
Boost Your Metabolism
Growth hormone production is stimulated by GHRP-2 and CJC-1295, which improves metabolism and calorie burning.
Goal Fat Reduction
Certain medications, like ipamorelin and tesamorelin, target fat deposits specifically and aid in body reshaping.
Gaining Muscle
Lean muscle mass development is aided by sermorelin and other growth hormone-related substances, which raises energy expenditure.
Combinatorial gut hormone therapy is one of the more promising strategies for identifying improved treatments for metabolic disease. Many approaches combine the established benefits of glucagon-like peptide-1 (GLP-1) agonism with one or more additional molecules with the aim of improving metabolic outcomes.
Recent attention has been drawn to the glucose-dependent insulinotropic polypeptide (GIP) system due to compelling pre-clinical evidence describing the metabolic benefits of antagonising the GIP receptor (GIPR). We rationalised that benefit might be accrued from combining GIPR antagonism with GLP-1 agonism. [1]
Do Peptides Help In Losing Weight?
Given the increasing rate of obesity, peptides offer great promise as a means of losing weight. A new approach to managing weight is given by recent studies on the ability of fat to burn calories. Because they are flexible chains of amino acids, peptides are essential in this situation. Peptides provide a potential way to improve calorie burning and better control weight by inducing white fat to resemble the metabolic activity of fat.
According to researchers, peptides may be useful in the treatment of metabolic illnesses. Their brief half-life guarantees effective absorption and low toxicity levels while reducing the possibility of long-term side effects. Because of these qualities, peptides are shown to be an effective weight loss method that can make major progress against obesity and improve metabolic health.
When obese or overweight people received cagrilintide (4.5 mg/week) in combination with semaglutide (2.4 mg/week), there was a 15.4% reduction in body weight at 20 weeks, and in a 32 week study in obese or overweight people with T2D, a combination of cagrilintide with semaglutide (each 2.4 mg/week) was associated with reductions in body weight (by 15.6%) and HbA1c (by 2.18%). [2]
Is Peptide Therapy Considered Safe?
Peptide therapy is usually regarded as safe and has few adverse effects. But, it’s crucial to work with a licensed healthcare provider and use the product as prescribed, just like with any medical procedure or supplement.
It is imperative that peptide therapy be customized to meet the certain requirements of each patient, closely monitored for safety, and updated with any new developments in science or technology.
Peptides have gained increased interest as therapeutics during recent years. More than 60 peptide drugs have reached the market for the benefit of patients and several hundreds of novel therapeutic peptides are in preclinical and clinical development. The key contributor to this success is the potent and specific, yet safe, mode of action of peptides. [3]
Different Types Of Peptides Fat Loss
There have been several peptides studied for their potential effects on fat metabolism. Here are some examples:
Wegovy (Semaglutide)
In clinical trials, an injectable drug that imitates a hormone involved in appetite regulation resulted in significant weight loss.
Ozempic (Semaglutide)
It is mostly used to treat type 2 diabetes, but it also helps people lose weight by decreasing and slowing stomach emptying.
Mounjaro (Tirzepatide)
A dual-action drug that targets the GIP and GLP-1 receptors has been shown in trials to have a significant weight loss impact.
Tirzepatide
Like Mounjaro, it works on several pathways to improve insulin sensitivity and encourage weight loss.
CJC 1295 / Ipamorelin
A mix of peptides that may help with both muscle gain and fat loss by stimulating the release of growth hormone.
BPC 157
A peptide with regenerative qualities that may promote muscle healing and recuperation, thereby helping with weight management.
Thymosin Beta 4
A peptide that promotes tissue regeneration and repair, it may help with weight loss and recovery from exercise.
Why Are Some Peptides Illegal?
Numerous peptides have been prohibited from use by athletes by organizations like the World Anti-Doping Agency due to the possibility of misuse. Additionally, as evidenced by the most recent draft guidance from CDER, the FDA is paying more attention to the manufacturing process for peptides.
Over the years, peptides have emerged among the many substances that are both touted as performance-enhancing, and increasingly included illegally in products available online. Peptide hormones, such as chorionic gonadotropin (CG) and luteinizing hormone (LH), may also be prescribed by a physician to treat various medical conditions.[4]
Peptides For Fat Loss
IV Vitamin Therapy offers the best peptides for fat loss near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.
References:
1. West JA, Tsakmaki A, Ghosh SS, et al. Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism. PloS one. 2021;16(3):e0249239-e0249239. doi:https://doi.org/10.1371/journal.pone.0249239
2.Bailey CJ, Flatt PR, J. Michael Conlon. An update on peptide-based therapies for type 2 diabetes and obesity. Peptides. 2023;161:170939-170939. doi:https://doi.org/10.1016/j.peptides.2023.170939
3. Keld Fosgerau, Hoffmann T. Peptide therapeutics: current status and future directions. Drug discovery today. 2015;20(1):122-128. doi:https://doi.org/10.1016/j.drudis.2014.10.003
4. Perishable. 6 Things to Know About Peptide Hormones and Releasing Factors | USADA. U.S. Anti-Doping Agency (USADA). Published September 15, 2020. Accessed May 28, 2024. https://www.usada.org/spirit-of-sport/education/6-things-know-peptide-hormones/